‘Family Guy’ and ‘American Dad’ creator Seth MacFarlane will be the emcee of the ‘Comedy Central Roast of Charlie Sheen.’

MacFarlane, who previously hosted roasts for Donald Trump and David Hasselhoff, seems confident Sheen’s well-documented foibles will make for a successful evening of comedy

“I’m very excited to work with Comedy Central again on the roast,” MacFarlane said. “Charlie is a true icon with a talent that is strong and pure and concentrated into small crystals which can be smoked or eaten.”

The roast will take place on September 10, but won’t air until September 19 — which just happens to be the same night that Ashton Kutcher makes his debut as Charlie Sheen’s replacement on ‘Two and a Half Man.’

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